A Survey of Protein Fold Recognition Algorithms
نویسندگان
چکیده
منابع مشابه
A Survey of Protein Fold Recognition Algorithms
Problem statement: Predicting the tertiary structure of proteins from their linear sequence is really a big challenge in biology. This challenge is related to the fact that the traditional computational methods are not powerful enough to search for the correct structure in the huge conformational space. This inadequate capability of the computational methods, however, is a major obstacle in fac...
متن کاملProtein Fold Recognition Algorithms-A General Survey
Protein folding is considered as a significant confrontation in biological and protein research. This confrontation is interrelated to the fact that the conventional computational approaches are not potent enough to search for the appropriate structure in the large conformational space of protein. This insufficiency of the computational methods is a major hindrance in facing the protein folding...
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In fold recognition by threading one takes the amino acid sequence of a protein and evaluates how well it fits into one of the known three-dimensional (3D) protein structures. The quality of sequence-structure fit is typically evaluated using inter-residue potentials of mean force or other statistical parameters. Here, we present an alternative approach to evaluating sequence-structure fitness....
متن کاملEnsemble classifier for protein fold pattern recognition
MOTIVATION Prediction of protein folding patterns is one level deeper than that of protein structural classes, and hence is much more complicated and difficult. To deal with such a challenging problem, the ensemble classifier was introduced. It was formed by a set of basic classifiers, with each trained in different parameter systems, such as predicted secondary structure, hydrophobicity, van d...
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ژورنال
عنوان ژورنال: Journal of Computer Science
سال: 2008
ISSN: 1549-3636
DOI: 10.3844/jcssp.2008.768.776